|
rs7873784
|
|
|
0.020 |
GeneticVariation |
BEFREE |
We hypothesize that additional functional PU.1 site may increase TLR4 expression in individuals carrying minor C variant of rs7873784 and modulate the development of certain pathologies, such as rheumatoid arthritis and type-2 diabetes mellitus.
|
31785408 |
2020 |
|
rs1800796
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Relationship between polymorphisms in -572G/C interleukin 6 promoter gene polymorphisms (rs1800796) and risk of rheumatoid arthritis: A meta-analysis.
|
31782615 |
2020 |
|
rs1143679
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Interestingly, the GACC haplotype, which carries the ITGAM rs1143679 (A) minor allele, showed an association with protection against RA (OR = 0.14 and p = 3.0x10-4).
|
31774828 |
2019 |
|
rs6822844
|
|
|
0.770 |
GeneticVariation |
BEFREE |
Overall, the IL-21 rs6822844 G/T polymorphism was found to be significantly associated with decreased RA risk (eg: T-allel</span>e vs. G-allele: OR= 0.81, 95% CI= 0.72-0.91, P < 0.001).
|
31763680 |
2020 |
|
rs2518723
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In addition, our results demonstrated that the rs944796 G allele, rs2518723 T allele, rs3217992 T allele frequencies were significantly associated with anti-CCP in RA patients (all <i>P</i> < 0.05).
|
31736958 |
2019 |
|
rs3217992
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In addition, our results demonstrated that the rs944796 G allele, rs2518723 T allele, rs3217992 T allele frequencies were significantly associated with anti-CCP in RA patients (all <i>P</i> < 0.05).
|
31736958 |
2019 |
|
rs944796
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In addition, our results demonstrated that the rs944796 G allele, rs2518723 T allele, rs3217992 T allele frequencies were significantly associated with anti-CCP in RA patients (all <i>P</i> < 0.05).
|
31736958 |
2019 |
|
rs755622
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The aim of this study was to evaluate the association of MIF promoter polymorphisms (-794CATT<sub>5-8</sub> rs5844572 and -173G > C, rs755622), circulating MIF levels, and mRNA expression with RA susceptibility and disease activity.
|
31701681 |
2020 |
|
rs5844572
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The aim of this study was to evaluate the association of MIF promoter polymorphisms (-794CATT<sub>5-8</sub> rs5844572 and -173G > C, rs755622), circulating MIF levels, and mRNA expression with RA susceptibility and disease activity.
|
31701681 |
2020 |
|
rs1689334
|
|
|
0.010 |
GeneticVariation |
BEFREE |
This study genotyped blood samples from 214 patients with rheumatoid arthritis (RA) and 293 healthy controls for single nucleotide polymorphisms (SNPs) rs2977537, rs2929970, rs2929973, rs2977530, rs1689334 and rs62514004.
|
31689765 |
2019 |
|
rs2929970
|
|
|
0.010 |
GeneticVariation |
BEFREE |
This study genotyped blood samples from 214 patients with rheumatoid arthritis (RA) and 293 healthy controls for single nucleotide polymorphisms (SNPs) rs2977537, rs2929970, rs2929973, rs2977530, rs1689334 and rs62514004.
|
31689765 |
2019 |
|
rs2929973
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We showed that RA disease was more likely with the AA genotype compared with the AG genotype of SNP rs2977537 (adjusted odds ratio [AOR]: 0.54; 95% confidence interval [CI]: 0.34-0.84), and with the TT genotype (AOR: 0.24; 95% CI: 0.13-0.39) or the GG genotype (AOR: 0.05; 95% CI: 0.03-0.10) compared with the GT genotype of rs2929973, and with the AA genotype (AOR: 0.34; 95% CI: 0.22-0.54) or GG genotype (AOR: 0.52; 95% CI: 0.31 to 0.87) vs the AG genotype of rs2977530.
|
31689765 |
2019 |
|
rs2977530
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We showed that RA disease was more likely with the AA genotype compared with the AG genotype of SNP rs2977537 (adjusted odds ratio [AOR]: 0.54; 95% confidence interval [CI]: 0.34-0.84), and with the TT genotype (AOR: 0.24; 95% CI: 0.13-0.39) or the GG genotype (AOR: 0.05; 95% CI: 0.03-0.10) compared with the GT genotype of rs2929973, and with the AA genotype (AOR: 0.34; 95% CI: 0.22-0.54) or GG genotype (AOR: 0.52; 95% CI: 0.31 to 0.87) vs the AG genotype of rs2977530.
|
31689765 |
2019 |
|
rs2977537
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We showed that RA disease was more likely with the AA genotype compared with the AG genotype of SNP rs2977537 (adjusted odds ratio [AOR]: 0.54; 95% confidence interval [CI]: 0.34-0.84), and with the TT genotype (AOR: 0.24; 95% CI: 0.13-0.39) or the GG genotype (AOR: 0.05; 95% CI: 0.03-0.10) compared with the GT genotype of rs2929973, and with the AA genotype (AOR: 0.34; 95% CI: 0.22-0.54) or GG genotype (AOR: 0.52; 95% CI: 0.31 to 0.87) vs the AG genotype of rs2977530.
|
31689765 |
2019 |
|
rs62514004
|
|
|
0.010 |
GeneticVariation |
BEFREE |
This study genotyped blood samples from 214 patients with rheumatoid arthritis (RA) and 293 healthy controls for single nucleotide polymorphisms (SNPs) rs2977537, rs2929970, rs2929973, rs2977530, rs1689334 and rs62514004.
|
31689765 |
2019 |
|
rs2476601
|
|
|
1.000 |
GeneticVariation |
BEFREE |
Results showed that 1858 C/T PTPN22 SNP significantly (P = 0.007, OR = 2.321, 95% CI = 1.063-5.067) associated with RA.
|
31669381 |
2019 |
|
rs26232
|
|
|
0.830 |
GeneticVariation |
BEFREE |
The rs26232 C allele, which has previously been associated with both the risk and severity of RA, is associated with greater invasive activity of RASFs in vitro, and with higher expression of ICAM-1 and IP-10.
|
31652652 |
2019 |
|
rs10106
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The aim of the study was to look for the association of FPGS 2752 G > A (rs1544105), FPGS 1994 A > G (rs10106), and GGH 452 C > T (rs 11545078), GGH -401C > T (rs 3758149) gene polymorphisms with methotrexate (MTX) treatment response and MTX-induced adverse events in South Indian Tamil patients with rheumatoid arthritis (RA).
|
31611592 |
2020 |
|
rs11545078
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The aim of the study was to look for the association of FPGS 2752 G > A (rs1544105), FPGS 1994 A > G (rs10106), and GGH 452 C > T (rs 11545078), GGH -401C > T (rs 3758149) gene polymorphisms with methotrexate (MTX) treatment response and MTX-induced adverse events in South Indian Tamil patients with rheumatoid arthritis (RA).
|
31611592 |
2020 |
|
rs1348254052
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The aim of the study was to look for the association of FPGS 2752 G > A (rs1544105), FPGS 1994 A > G (rs10106), and GGH 452 C > T (rs 11545078), GGH -401C > T (rs 3758149) gene polymorphisms with methotrexate (MTX) treatment response and MTX-induced adverse events in South Indian Tamil patients with rheumatoid arthritis (RA).
|
31611592 |
2020 |
|
rs1544105
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The aim of the study was to look for the association of FPGS 2752 G > A (rs1544105), FPGS 1994 A > G (rs10106), and GGH 452 C > T (rs 11545078), GGH -401C > T (rs 3758149) gene polymorphisms with methotrexate (MTX) treatment response and MTX-induced adverse events in South Indian Tamil patients with rheumatoid arthritis (RA).
|
31611592 |
2020 |
|
rs3763959
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The AG genotype (rs3763959) has been associated with a higher presence of bone erosion in RA patients.
|
31600237 |
2019 |
|
rs4239242
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The rs4239242</span> TT genotype showed a positive association with RA (p = 0.0032, odds ratio = 0.28), and heterozygous TC were prevalent in the control group compared to RA patients (p = 0.0001, odds ratio = 7.99).
|
31600237 |
2019 |
|
rs10088748
|
|
|
0.700 |
GeneticVariation |
GWASCAT |
Genetic associations with radiological damage in rheumatoid arthritis: Meta-analysis of seven genome-wide association studies of 2,775 cases.
|
31596875 |
2019 |
|
rs112112734
|
|
|
0.700 |
GeneticVariation |
GWASCAT |
Genetic associations with radiological damage in rheumatoid arthritis: Meta-analysis of seven genome-wide association studies of 2,775 cases.
|
31596875 |
2019 |